Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 11 - Jul 16
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
PSAP Recombinant Rabbit mAb (S-2399-11)Product Specification Host Rabbit Antigen PSAP Synonyms Prosaposin; Proactivator polypeptide; GLBA; SAP1 Immunogen Synthetic Peptide Location Lysosome Accession P07602 Clone Number S 2399 11 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample PANC 1, PC 3, HeLa Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0.
Product Specification
| Host | Rabbit |
| Antigen | PSAP |
| Synonyms | Prosaposin; Proactivator polypeptide; GLBA; SAP1 |
| Immunogen | Synthetic Peptide |
| Location | Lysosome |
| Accession | P07602 |
| Clone Number | S-2399-11 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Positive Sample | PANC-1, PC-3, HeLa |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:250 | Hu |
Background
Prosaposin (PSAP) is a highly conserved, 68- to 73-kDa glycoprotein encoded by the PSAP gene on chromosome 10q22.1 that serves dual intracellular and extracellular roles: inside the endolysosomal system it is proteolytically cleaved into four small lysosomal activator proteins (saposins A–D) that bind either specific hydrolases or their glycosphingolipid substrates to enable sphingolipid catabolism, while outside the cell PSAP acts as a secreted neurotrophic factor that supports neuronal survival, neurite outgrowth and ERK signaling, can be endocytosed via LRP1 or CI-M6PR, and has recently been implicated in cancer progression, metastasis and as an emerging therapeutic target in tumors.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy